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Long-term stimulation by implanted pacemaker enables non-atrophic treatment of vocal fold paresis in a human-like animal model

Kassandra Walluks, Bianca Hoffmann, Carl-Magnus Svensson, Gerhard Förster, Andreas H. Müller, Justin Perkins, Marc Thilo Figge, Dirk Arnold

Open access


Unique target binding by the C-terminal region of FHR1 provides a new perception for aHUS Pathology

Perie L, Stippa S, Saffer C, Hartmann A, Mörgelin M, Zipfel SLH, Figge MT, Wiech T, Skerka C, Zipfel PF


Open access


IMFSegNet: Cost-effective and objective quantification of intramuscular fat in histological sections by deep learning

Jan-Philipp Praetorius, Kassandra Walluks, Carl-Magnus Svensson, Dirk Arnold, Marc Thilo Figge


Open access


Surrogate infection model predicts optimal alveolar macrophage number for clearance of Aspergillus fumigatus infections

Saffer C, Timme S, Rudolph P, Figge MT

Nature Systems Biology and Application

Open access


JIPipe: A graphical batch processing language for ImageJ

Ruman Gerst, Zoltán Cseresnyés,Marc Thilo Figge

Open access


Toxin-producing endosymbionts shield pathogenic fungus against micropredators.

Richter, I., Radosa, S., Cseresnyés, Z., Ferling, I., Büttner, H., Niehs, S.P., Gerst, R., Figge, M.T., Hillmann, Falk, Hertweck, C.

mBio xxx, xxx DOI: xxx

Open access


Bacterial endosymbionts protect beneficial soil fungus from nematode attack.

Büttner H*, Niehs SP*, Vandelannoote K, Cseresnyés Z, Dose B, Richter I, Gerst R, Figge MT, Stinear TP, Pidot SJ, Hertweck C

PNAS 118, 37.

Open access


Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection.

Hoang, T. *, Cseresnyés, Z.*, Hartung, S.*, Blickensdorf, M., Saffer, C., Rennert, K., Mosig, A.S, von Lilienfeld-Toal, M.#+, Figge, M.T.#+

Biomaterials 283, 121420 DOI: https://doi.org/10.1016/j.biomaterials.2022.121420

Open access


Stealth Effect of Oligo(2-Ethyl-2-Oxazolines) in Graft Copolymers: Minor Changes of Backbone End Group Determine Cell-Type Specificity in the Liver.

Muljajew I*, Huschke S*, Ramoji A, Cseresnyés Z, Hoeppener S, Nischang I, Foo W, Popp J, Figge MT, Weber C, Bauer M, Schubert U, Press A

ACS Nano 15(7), 12298-313.

Open access


Enhanced segmentation of label-free cells for automated migration and interaction tracking

Belyaev I, Praetorius JP, Medyukhina A, Figge MT

Cytometry Part A

Requires a password for access


Comparative assessment of immune evasion mechanisms in human whole-blood infection assays by a systems biology approach.

Lehnert T, Prauße MTE, Hünniger K, Praetorius JP, Kurzai O, Figge MT

PLoS One 16(4), e0249372

Requires a password for access


Dynamic spherical harmonics approach for shape classification of migrating cells.

Medyukhina A*, Blickensdorf M*, Cseresnyés Z, Ruef N, Stein JV, Figge MT

Sci Rep 10(1), 6072.

Open access


Automated tracking of label-free cells with enhanced recognition of whole tracks

Al-Zaben N*, Medyukhina A*, Dietrich S, Marolda A, Hünniger K, Kurzai O, Figge MT

Sci Rep 9(1), 3317

Requires a password for access


Predictive virtual infection modeling of fungal immune evasion in human whole blood.

Prauße MTE, Lehnert T, Timme S, Hünniger K, Leonhardt I, Kurzai O, Figge MT

Front Immunol 9, 560.

Requires a password for access


Dimensionality of motion and binding valency govern receptor-ligand kinetics as revealed by agent-based modeling.

Lehnert T, Figge MT

Front Immunol 8, 1692.

Open access


Untangling cell tracks: Quantifying cell migration by time lapse image data analysis.

Svensson CM, Medyukhina A, Belyaev I, Al-Zaben N, Figge MT

Cytometry A 93(3), 357-370

Open access


Hessian-based quantitative image analysis of host- pathogen confrontation assays

Cseresnyes Z*, Kraibooj K*, Figge MT

Cytometry A 93(3), 346-356

Requires a password for access


Automated quantification of early bone alterations and pathological bone turnover in experimental arthritis by in vivo PET/CT imaging

Hoffmann B*, Svensson C-M*, Straßburger M, Gebser B, Irmler IM, Kamradt T, Saluz HP, Figge MT

Sci Rep 7, 2217

Requires a password for access


Fully automated evaluation of total glomerular number and capillary tuft size in murine nephritic kidneys using lightsheet microscopy.

Klingberg A, Hasenberg A, Ludwig-Portugall I, Medyukhina A, Männ L, Brenzel A, Engel DR, Figge MT, Kurts C, Gunzer M

J Am Soc Nephrol 28(2), 452-459

Requires a password for access


Segmentation of clusters by template rotation expectation maximization.

Svensson C-M, Bondoc K G, Pohnert G, Figge MT

Comput Vis Image Underst 152, 64-72.

Open access